The invention discloses application of a paeoniflorin compound or pharmaceutically acceptable salt, solvates, polymorphism, antipode or racemic mixture in preparation of drugs for preventing and/or curing tumors. Preferably, the paeoniflorin compound is chosen from albiflorin and/or paeoniflorin, and the tumors are solid tumors. Experiments in vitro and in vivo show that the paeoniflorin compound has exact anti-tumor activity, and a new anti-tumor drug is expected to be developed so as to provide new choices for clinical cancer treatment.
