A analgesic composition for topical application is provided that includes magnesium sulfate and a source of vitamin B12 in an amount effective for providing pain relief associated with peripheral neuropathy. The composition has a viscosity effective for allowing topical application of the composition to an afflicted area where the magnesium sulfate and vitamin B12 is absorbed through the dermis to the subcutaneous to provide pain relief relating to symptoms of peripheral neuropathy. The composition provides the novel benefits of being portable, easily dispensed, and provides a higher concentration of applied magnesium sulfate and vitamin B12 than the traditional dispensing method of Epsom Salt soaking solutions.