COMPOSITIONS COMPRISING COFORMULATION OF ANTI-PD-L1 AND ANTI-CTLA-4 ANTIBODIES

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专利权人:

MedImmune; LLC

发明人:

Jiali DU,Ambarish Shah

申请号：

US15495388

公开号：

US20170306025A1

申请日:

2017.04.24

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Provided herein are compositions comprising coformulation of anti-PD-L1 and anti-CTLA-4 antibodies, or antigen-binding fragments thereof, and methods of making and using such compositions. In various aspects, stable coformulations of the anti-PD-L1 antibody durvalumab (MEDI4736) and the anti-CTLA-4 antibody tremelimumab are provided.

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