Kyoto University;The Regents of the University of California
发明人:
申请号：
EP13851788.3
公开号：
EP2915881A1
申请日:
2013.10.31
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
The present invention provides a non-human animal IKKβ which shows fibrosis of tissue, since it lacks IKKβ gene in a myofibroblast- and/or smooth muscle cell-specific manner. Since the non-human animal shows pathology highly similar to scleroderma, it is extremely useful as an animal model of scleroderma.
