The invention relates to a joint prosthesis component (200) adapted to be fixed to a first bone extremity (250) of a joint of a single patient having compromised anatomy, said joint prosthesis component (200) comprises: - at least one fastening portion (202, 205, 206, 207) adapted to be in contact with the first bone extremity； - at least one joint portion (4) adapted to be directly coupled with a second bone extremity of the joint or with a conjugate second joint prosthesis component, in turn fixed to the second bone extremity. Advantageously, the fastening portion is at least partially customized to be specifically shaped with respect to the morphology of the first bone extremity processed by means of at least one surgical instrumentation.
