Koc-Kan Ho,Yong Xu,Michael David Saunders,Xiaohui Liu,Scott Albert Pearce,Kevin Bret Wright,Jason Marc Foulks,Kenneth Mark Parnell,Steven Brian Kanner,David Lee Vollmer,Jihua Liu
申请号：
US15183581
公开号：
US10207996B2
申请日:
2016.06.15
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Compounds having activity as PKM2 activators are disclosed. The compounds have the following structure (I):including stereoisomers, tautomers, pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R3, R4, R5 and R6 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
