The invention relates to a composition of water-soluble ingredients (CWSI) which when solubilized in water (W) and either in the presence of a wetting agent and/or in the presence of at least one agriculturally acceptable solvent, forms a synergistic composition useful for the control of pathogens and/or the prevention of diseases associated with the presence of said pathogens in and/or on seeds. Said composition of water-soluble ingredients (CWSI) comprises at least one oxidizer in liquid form or solid form, or a precursor thereof in liquid or solid form, said at least one agriculturally acceptable solvent is soluble in water (W)； the water-soluble ingredients (CWSI) is dissolved in the water (W), in a weight ratio (CWSI)/(W) ranging from 1:100 to 1:4, and when present, said at least one agriculturally acceptable solvent represents from 2 % by volume to 70 % by volume of the total volume of the synergistic composition to be formed. The invention also relates to a synergistic composition for the control of pathogens and/or the prevention of diseases associated with the presence of said pathogens in and/or on seeds, and a method and a use of the same.
