This disclosure describes a biological system of plant growth promotion, pest resistance and disease resistance by application of strains of T. viride, Trichoderma harzianum K2, Bacillus amyloliquifaciens AS2, Bacillus amyloliquifaciens AS3, or a combination thereof. These strains can be used in conventional or organic agriculture for the promotion nematode resistance when applied topically as a foliar spray or as a seed coating. The highly active strains also are expected to increase plant productivity and improve quality of fruits, vegetables, flowers or other plant products.