GOEHRING, RICHARD R.,TAFESSE, LAYKEA,YAO, JIANGCHAO
申请号:
CA2905678
公开号:
CA2905678A1
申请日:
2014.03.14
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention is directed to Buprenorphine Analog compounds of Formula (I), (II) or (III) and including various stereoisomers (such as Formula (IA) shown below), wherein R1, R3a, R3b, R16, R15, G, Q, X, and Z are as defined herein. Compounds of the Invention are useful for treating pain, constipation, and other conditions modulated by activity of opioid and ORL-1 receptors.