GEOVAX INC EMORY UNIVERSITY;THE GOVERMENT OF THE UNITED STATES/NIH AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMA;US GOV NAT INST HEALTH
发明人:
ROBINSON HARRIET L,MOSS BERNARD,WYATT LINDA S
申请号：
AP2012006258
公开号：
AP2012006258A0
申请日:
2010.10.13
申请国别(地区):
AP
年份:
2012
代理人:
摘要：
Methods for eliciting beneficial immune responses against HIV by administering to a subject a recombinant MVA virus expressing HIV env, gag, and pol antigens are described. The recombinant MVA is administered at least three times and, in certain embodiments, is administered to a patient that has not been treated with a DNA vaccine directed against HIV (i.e., has not been treated with a nucleic acid molecule encoding one or more HIV antigens). The methods can elicit production IgA antibodies directed against HIV in rectal secretions of a treated subject.
