THE REGENTS OF THE UNIVERSITY OF COLORADO; A BODYCORPORATE
发明人:
YIN, HANG,CHENG, KUI
申请号：
EP13826030
公开号：
EP2879669A4
申请日:
2013.07.29
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
Provided are compounds, compositions and methods for treating Toll-like receptor 1/2 complex (TLRI/2) related inflammatory disorders. Small molecules, based on the benzotropolone scaffold, capable of influencing downstream signaling are disclosed as well as methods of making and modifying these molecules. Also provided are methods for treating a subject for a clinical condition associated with Toll-like receptor complex 1/2 activation, comprising administering to the subject an effective amount of a benzotropolone compound.
