PROBLEM TO BE SOLVED: To obtain a medicine composition for treating or preventing various autoimmune diseases caused by the activation of lymphocytes such as T-cells, allergic diseases or inflammatory diseases (e.g. arthropathy such as articular rheumatism or osteoarthritis), pathology following various transplantations (e.g. graft-versus-host disease or transplantation immunity rejection), various inflammations (e.g. hepatitis or inflammatory enteric disease), disease symptoms due to overproduction of antibody against an extraneous antigen, which is induced by immunization therewith.SOLUTION: An antibody against AILIM(activation inducible lymphocyte immunomodulatory molecule) has a significant treating effect on the above various arthropathia, pathology following transplantation, various inflammations and disease symptoms due to overproduction of the antibody against the extraneous antigen.COPYRIGHT: (C)2002,JPOAntistoff mot AILIM (alternativt betegnet JTT-1 -antigen, JTT-2-antigen, ICOS og 8F4) ble funnet å ha en signifikant terapeutisk virkning på art rose, f.eks. reumatoid art ritt og osteoartritt, "graft versus host"-sykdom, transplantatimmunrejeksjon, inflammasjon (hepatitt og inflammatoriske tarm- sykdommer) og sykdomstilstander forbundet med overdreven produksjon av et antistoff mot et fremmed antigen, utløst ved immunologisk sensitivisering med antigenet.