Willem Frederik Johan Karstens;Paolo Giovanni Martino Conti;Cornelis Marius Timmers;Ralf Plate;Christianus Johannes Van Koppen
发明人:
Willem Frederik Johan Karstens,Paolo Giovanni Martino Conti,Cornelis Marius Timmers,Ralf Plate,Christianus Johannes Van Koppen
申请号:
US12675012
公开号:
US09174940B2
申请日:
2008.08.28
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates the use of a compound, a pharmaceutical composition, compounds and a kit for treating or preventing disorders in a mammal responsive to TSH receptor mediated pathways, including disorders such as hyperthyroidism, Graves' disease, Graves Ophthalmopathy, Graves' associated pretibial dermopathy, nodular goitre and thyroid cancer comprising administering to said mammal an effective amount of a tetrahydroquinoline compound of Formula (I) or an pharmaceutically acceptable salt thereof.