Paul MOLLARD,Christopher R. CORNELL,Kieron E. WESSON,Peter GIANNOUSIS,Shazad SUCHIT,Mahmoud MIRMEHRABI
申请号:
US16354070
公开号:
US20190307706A1
申请日:
2019.03.14
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Disclosed herein are polymorphic and amorphous forms of anhydrate, hydrate, and solvates of (R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide and methods of using such compositions for treating or suppressing oxidative stress disorders, including mitochondrial disorders, impaired energy processing disorders, neurodegenerative diseases and diseases of aging. Further disclosed are methods of making such polymorphic and amorphous forms.