WANG, GUOQIANG,HE, YONG,GRANGER, BRETT,XING, XUECHAO,OR, YAT SUN
申请号：
CA3058754
公开号：
CA3058754A1
申请日:
2018.04.09
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention relates to processes for preparing compounds of Formula (I) and compounds of Formula (II) or a pharmaceutically acceptable salt or solvate thereof. These compounds and pharmaceutical compositions are useful as FXR or TGR5 modulators. Specifically, the present invention relates to bile acid derivatives and methods for their preparation and use. The present invention relates to a process for the preparation of the compounds of Formula (III), Formula (IV), Formula (V), and Formula (VI), The present invention also relates to a process for the preparation of compounds (VII), (VIII) and (IX).
