PROCÉDÉ DE PRODUCTION D'UNE CELLULE CULTIVÉE, ET PROCÉDÉ DE PRODUCTION D'UN AGENT THÉRAPEUTIQUE POUR UNE MALADIE DE LÉSION DE LA MOELLE ÉPINIÈRE

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专利权人:

Regenesis Science Co.; Ltd.

发明人:

申请号：

EP18876286.8

公开号：

EP3708662A1

申请日:

2018.08.02

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

[Problem to Be Solved] The present invention is to provide a method of culturing a cell, which method safely increases GDNF mRNA expression without introducing a gene with a virus.[Means to Solve the Problem] A method of producing a cultured cell comprising glial cell line-derived neurotrophic factor (GDNF) mRNA, comprising the step of culturing a human skin-derived stem cell in a serum-free medium comprising at least one of SAG, purmorphamine and sonic hedgehog (SHH) protein. The medium may further comprise B-27 supplement, a ROCK inhibitor, EGF and FGF2.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/