In an ultrasound imaging system, an ultrasound scanning assembly (USC) provides volume data (VD) resulting from a three- dimensional scan of a body (BDY). A region of interest detector (RDT) detects a region within the volume data (VD) characterized by a variation of at least one data parameter, which exceeds a margin. A slice generator (SLG) may then generate slices (SX) from the region that has been detected. These slices (SX) can be displayed on a display device (DPL).