Istituto Di Ricerche Di Biologia Molecolare P. Angeletti SpA
发明人:
Ontoria Ontoria, Jesus Maria,Schultz-Fademrecht, Carsten,Jones, Philip,Scarpelli, Rita
申请号：
AU2008204380
公开号：
AU2008204380B2
申请日:
2008.01.08
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
The present invention relates to compounds of formula (I): and pharmaceuticallyacceptable salts, stereoisomers or tautomers thereof which are inhibitorsof poly (ADP-ribose) polymerase (PARP) and thus useful for the treatment of cancer,inflammatory diseases, reperfusion injuries, ischemic conditions, stroke,renal failure, cardiovascular diseases, vascular diseases other than cardiovasculardiseases, diabetes, neurodegenerat ive diseases, retroviral infection, retinaldamage or skin senescence and UV- induced skin damage, and as chemo- and/or radiosensitizersfor cancer treatment.
