EDUCATIONAL FOUNDATION JICHI MEDICAL UNIVERSITY;OTSUKA PHARMACEUTICAL CO., LTD.
发明人:
YOSHIDA, SHIGETO,SUDO, TOSHIKI
申请号:
MYPI 20080355
公开号:
MY148135A
申请日:
2006.11.02
申请国别(地区):
MY
年份:
2013
代理人:
摘要:
THE INVENTION PROVIDES A PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE POLYPEPTIDE OF THE FOLLOWING (A) TO (D) 5 (A) A POLYPEPTIDE COMPRISING THE AMINO ACID SEQUENCE OF SEQ ID NO:1; (B) A POLYPEPTIDE COMPRISING AN AMINO ACID SEQUENCE COMPRISING ONE OR MORE AMINO ACID DELETIONS, INSERTIONS, SUBSTITUTIONS OR ADDITIONS IN THE AMINO ACID SEQUENCE OF THE ABOVE (A) AND HAVING A PLATELET AGGREGATION INHIBITORY ACTIVITY AND/OR A PLATELET ADHESION INHIBITORY ACTIVITY; (C) A POLYPEPTIDE COMPRISING THE AMINO ACID SEQUENCE OF SEQ ID NO:3; AND (D) A POLYPEPTIDE COMPRISING AN AMINO ACID SEQUENCE COMPRISING ONE OR MORE AMINO ACID DELETIONS, INSERTIONS, SUBSTITUTIONS OR ADDITIONS IN THE AMINO ACID SEQUENCE OF THE ABOVE (C) AND HAVING A PLATELET AGGREGATION INHIBITORY ACTIVITY AND/OR A PLATELET ADHESION INHIBITORY ACTIVITY, AS AN ACTIVE COMPONENT.