A medical diagnostic system may include a plurality of blood pressure measuring devices each configured to measure blood pressure of a respective extremity from among a plurality of extremities of a patient, and a blood pressure diagnostic device including at least one input device and a controller. The controller may cooperate with the at least one input device to determine blood pressure measurements for the respective patient extremities based upon the plurality of blood pressure measuring devices, receive an indicator of at least one symptom of the patient via the input device, and determine statistical probabilities that a condition of the patient is within a first group of vascular conditions requiring a first course of treatment, and a second group of vascular conditions requiring a second course of treatment different than the first course of treatment, based upon the determined blood pressure measurements and the indicator of the at least one symptom.
