Baker IDI Heart and Diabetes Institute Holdings Limited
发明人:
Peter, Karlheinz
申请号:
AU2006265782
公开号:
AU2006265782B2
申请日:
2006.07.05
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention provides an anticoagulant agent including a first elementcapable of inhibiting coagulation and a second element capable of targetingan activated platelet wherein upon administration of the agent to a subject thesecond element directs the first element to the activated platelet. Also providedis a probe for detecting a blood vessel abnormality including (a) a binding elementcapable of targeting an activated platelet and (b) a label. Applicant has shownthat agents and probes directed to activated platelets are useful in the diagnosisand therapy of coagulation disorders.