Jason Jingxin ZHANG;Hailin YANG;Sethumadhavan DIVAKARAMENON;WAVE LIFE SCIENCES;Chandra VARGEESE;Genliang LU;Naoki IWAMOTO;Subramanian MARAPPAN;Maria David FRANK-KAMENETSKY;David Charles Donnell BUTLER
发明人:
Chandra Vargeese,Jason Jingxin Zhang,Sethumadhavan Divakaramenon,David Charles Donnell Butler,Genliang Lu,Naoki Iwamoto,Hailin Yang,Maria David Frank-Kamenetsky,Subramanian Marappan
申请号:
US16098658
公开号:
US20190249173A1
申请日:
2017.05.03
申请国别(地区):
US
年份:
2019
代理人:
摘要:
In some embodiments, the present disclosure pertains to compositions and methods related to delivery of a biologically active agent, wherein the compositions comprise a biologically active agent and a lipid. In various embodiments, the lipid is selected from: lauric acid, myristic acid, palmitic acid, stearic acid, oleic acid, linoleic acid, alpha-linolenic acid, gamma-linolenic acid, docosa-hexaenoic acid (cis-DHA), turbinaric acid and dilinoleyl. In some embodiments, a composition and method are useful for delivery of a biologically active agent to a particular cell or tissue, e.g., a muscle cell or tissue.