Drug delivery devices for selecting and dispensing a number of doses of a medicament are provided. The drug delivery device includes a medicament reservoir attached to a housing, a drive mechanism including a plunger axially movable relative to the housing for dispensing doses of the medicament from the medicament reservoir, a dose selecting element releasably coupled to the drive mechanism and rotatable relative to the housing in a first direction for selecting a dose, a trigger axially movable relative to the housing for initiating dispensing of a dose selected by the dose selecting element, and a limiter selectively permitting and preventing axial movement of the trigger depending on the amount of the selected dose.