ONE POT SYNTHESIS OF 18F LABELEDTRIFLUOROMETHYLATED COMPOUNDS WITH DIFLUORO(IODO)METHANE

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专利权人:

发明人:

Thomas Rühl,Patrick Riss,Waqas Rafique

申请号：

US14624158

公开号：

US20150239796A1

申请日:

2015.02.17

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention relates to compositions and methods for the synthesis of 18F labeled compounds. In particular, the present invention relates to a copper (I) mediated one pot method for 18F-trifluoromethylation of aromatic- or heteroaromatic halides with difluoro(iodo)methane (e.g., for use at PET imaging agents).

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