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Human anti NGF neutralizing antibodies as Selective inhibitors of the Route of NGF
专利权人:
AMGEN INC.;MEDAREX, INC
发明人:
WILD KENNETH D,TREANOR JAMES J S,HUANG HAICHUM,INOUE HEATHER,ZHANG TIE J,MARTIN FRANK
申请号:
CO12075923
公开号:
CO6541558A2
申请日:
2012.05.09
申请国别(地区):
CO
年份:
2012
代理人:
摘要:
This Invention provides Antibodies that interact with Nerve Growth Factor (NGF Neive is human growth factor) or bind to and Neutralize him, therefore, the role of NGF. The Invention also provides Pharmaceutical compositions of said Antibodies and Methods for neutralizing the role NGF and, particularly, to treat Disorders associated with NGF (e.g.Chronic Pain), Managing a pharmaceutically effective amount of anti NGF Antibodies. Also provided are methods of detecting the amount of NGF in a sample using anti NGF Antibodies.Esta invención provee anticuerpos que interactúan con el factor de crecimiento nervioso (NGF ê neive growth factor) humano o se unen a él y, por consiguiente, neutralizan la función del NGF. La invención proporciona además composiciones farmacéuticas de los citados anticuerpos y métodos para neutralizar la función NGF y, particularmente, para tratar trastornos relacionados con NGF (v.g., dolor crónico) administrando una cantidad farmacéuticamente efectiva de anticuerpos anti-NGF. Se ofrecen asimismo métodos de detectar la cantidad de NGF en una muestra usando anticuerpos anti-NGF.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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