PHARMACEUTICAL COMPOSITION FOR INHIBITING RESISTANCE AGAINST ANTICANCER DRUGS OF PATIENT SUFFERING FROM OVARIAN CANCER COMPRISING NAG-1 INHIBITOR AS ACTIVE INGREDIENT
PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION
发明人:
Yuseok MOON,Ki Hyung KIM
申请号：
US15742525
公开号：
US20180200283A1
申请日:
2016.07.08
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A pharmaceutical composition includes an NAG-1 inhibitor as an active ingredient for inhibiting resistance against an anticancer drug of an ovarian cancer patient and a method of diagnosing prognosis of resistance against an anticancer drug of an ovarian cancer patient by using the NAG-1 inhibitor. It is found by controlling NAG-1 protein that NAG-1, which is overexpressed in an ovarian cancer patient and in an ovarian cancer stem cell having resistance against an anticancer drug, plays a key role in a chronic inflammatory reaction and resistance against an anticancer drug, and in this regard, NAG-1 can be used as a target gene for effective tumor therapy.
