GABRIELE, PETER D.,HARRIS, JEREMY J.,NICHOLSON, CHARLES BRENDAN,LU, STEVEN,GINN, BRIAN
申请号：
CA3088889
公开号：
CA3088889A1
申请日:
2019.01.17
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
A pH-modulating poly(glycerol sebacate) composition includes poly(glycerol sebacate) and at least one pH-modulating agent associated with the poly(glycerol sebacate). A process of making a pH-modulating poly(glycerol sebacate) composition includes forming a poly(glycerol sebacate) by a water-mediated reaction from glycerol and sebacic acid and associating at least one pH-modulating agent with the poly(glycerol sebacate). A process of modulating a pH of a buffered aqueous solution includes placing a pH-modulating poly(glycerol sebacate) composition in a buffered aqueous solution. The pH-modulating agent is released into the buffered aqueous solution during degradation of the poly(glycerol sebacate) to reduce a decrease in pH of the buffered aqueous solution caused by degradation of the poly(glycerol sebacate).
