Sharada Labadie,Jun Li,Jun Liang,Daniel Fred Ortwine,Xiaojing Wang,Jason Zbieg,Birong Zhang,Nicholas Charles Ray,Simon Goodacre,Jiangpeng Liao
申请号:
US15623904
公开号:
US20180002344A1
申请日:
2017.06.15
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Described herein are heteroaryl compounds with estrogen receptor modulation activity or function having the Formula I, II, and III structures:andstereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I, II, and III compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.