SITE-SPECIFIC ATTACHMENT OF DRUGS OR OTHER AGENTS TO ENGINEERED ANTIBODIES WITH C-TERMINAL EXTENSIONS

• 收藏
• 分享

专利权人:

发明人:

申请号：

EP08798164.3

公开号：

EP2185188B1

申请日:

2008.08.19

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

The present invention provides antibodies (e.g., IgG antibodies) having C-terminal cysteine-containing extensions that facilitate antibody conjugation to a partner molecule (e.g. a drug, toxin, marker molecule, protein, radioisotope, or other therapeutic agent). Methods of making, screening and selecting the antibodies of the invention are provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/