Javier Gordon OGEMBO,Lorraine Zvichapera MUTSVUNGUMA
申请号：
US16647705
公开号：
US20200276295A1
申请日:
2018.09.16
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Disclosed are vaccine compositions comprising a VLP comprising two or more EBV envelope glycoproteins and one or more T cell antigens and methods of preventing or treating EBV infections using the vaccine compositions. Also disclosed is an expression system or a single expression vector for co-expressing two or more EBV envelope glycoproteins simultaneously to generate a VLP vaccine. The expression system may include a single vector inserted with two or more nucleic acid sequences that encode two or more EBV envelope glycoproteins linked by one or more linking sequences such that the EBV envelope glycoproteins are co-expressed simultaneously.
