A monitoring system is presented, configured for use in monitoring heart condition of a subject. The system comprises: a receiver utility for receiving input data comprising data corresponding to signals continuously collected from the subject over time N and being indicative of a sequence of heart sounds； and a processing utility configured and operable for processing said input data to determine data indicative of heart condition of the subject. The processing comprises: identifying within said input data a sequence of acoustic signals corresponding to heart sounds comprising S1 signals corresponding to ventricular contraction and S2 signals corresponding to end of ventricular systole； analyzing the sequence of acoustic signals in accordance with parameters including signal periodicity, amplitude of S1 and S2 sounds, and intervals between S1 and S2 sounds within the collected sequence； and generating data indicative of cardiac condition of the subject in accordance with the analyzed data.
