A pharmaceutical carrier for recognizing carcinoma expressing fibronectin (FN) is disclosed, which includes: a drug carrier and a polypeptide connected to the surface of the drug carrier, wherein the polypeptide contains an FN-binding domain in Dipeptidyl peptidase IV (DPP IV). A pharmaceutical composition for treating carcinoma is also disclosed, which includes: the abovementioned pharmaceutical carrier and an active drug contained in the pharmaceutical carrier and used for treating carcinoma, wherein FN is expressed on the surfaces of the malignant carcinoma cells.本發明係有關於一種辨識表現纖維粘連蛋白(fibronectin,FN)之癌細胞之醫藥載體,包括:一藥物載體;以及一多肽(polypeptide),連接該藥物載體表面,其中,該多肽包含二肽基肽酶IV(dipeptidyl peptidase IV)之纖維粘連蛋白結合區塊(fibronectin-binding domain,FN-binding domain)。本發明亦關於一種用於治療轉移性癌細胞之醫藥組成物,包括:上述醫藥載體;以及一活性藥物,包含於該醫藥載體中且其係用於治療癌細胞,其中,該癌細胞表面係表現有纖維粘連蛋白。
