PARK, KWANG SUNG;박광성;박인규;PARK, IN KYU;PARK; KWANG SUNG
发明人:
PARK, KWANG SUNGKR,박광성,PARK, IN KYUKR,박인규
申请号：
KR1020170170159
公开号：
KR1020170142961A
申请日:
2017.12.12
申请国别(地区):
KR
年份:
2017
代理人:
摘要：
The present invention relates to a carrier of a vaginal lubrication drug. More specifically, the present invention relates to amphiphilic polymeric micelles for delivering a drug to a vaginal mucosa and a micelle-drug complex encapsulating retinoic acid which regulates water and glycerol secretion of a vaginal mucosa epithelium. Polymeric micelle nanoparticles for delivering the vaginal lubrication drug have a core-shell structure which is composed of amphiphilic copolymers in which a hydrophilic block composed of hyaluronic acid (HA) and a hydrophobic block composed of amine based compounds are conjugated.COPYRIGHT KIPO 2018본 발명은 질윤활용 약물의 전달체에 관한 것으로, 보다 구체적으로는 질점막에 약물을 전달하기 위한 양친성 고분자 미셀 및 이에 질점막상피의 수분 및 글리세롤 분비를 조절하는 레티노산을 봉입한 미셀-약물 복합체에 관한 것이다.
