An apparatus applicable for the ligation of internal tissue in a created or naturalcavity in animals or in the human body fx varicose veins in the gullet or a duodenaldiverticulum by means of an elastic band (19) while observing the legations throughan endoscope comprises : an automatic trigger unit (1) mounted firmly on the handleof the endoscope which subsequently can release a number of elastic bands (19)with the aid of a single stranded trigger cord (11). Hereby is achieved that onlya single elastic band (19) is released for each ligation and the establishmentof an one-man-operated equipment.