The present invention provides a pressure pulse wave sensor capable of ensuring sufficient durability in the case of wearing the sensor for a long time and capable of suppressing manufacturing cost and a biological information measurement device equipped with this sensor. The pressure pulse wave sensor 10 is equipped with sensor chips 22 having pressure detection elements 24; a substrate 50 to which the sensor chips 22 are fixed; a protection cover 40 for protecting the substrate 50 and the sensor chips 22. The outer peripheral face of the protection cover 40 has a top face 41 that is disposed above the pressure detection elements 24 in the Z-direction perpendicular to the detection faces 26 of the sensor chips 22 and is parallel with the detection faces 26. In the protection cover 40, opening sections 42 passing through from the positions of the top face 41 opposed to the detection faces 26 toward the detection faces 26 are formed, and the space between the opening sections 42 and the detection faces 26 is filled with a filling material 55.