'' GRANULAR MATERIAL, DETERMINATION FOR A DOSAGE FORM, DOSAGE FORM, DIRECT COMPRESSION PROCESS FOR PREPARING A DOSAGE FORM, USE OF GRANULAR MATERIAL AND PROCESS FOR GRANULATING A POLYMER POWDER ''
TIM D. CABELKA,AKSHAY BELLARE,KA CHUN .A CHAN,TINA P. DASBACH,KACEE B. ENDER,KARL V.JACOB,ROBERT E.SCHEID
申请号：
BRPI0809282
公开号：
BRPI0809282A2
申请日:
2008.02.28
申请国别(地区):
BR
年份:
2014
代理人:
摘要：
A dosage form for controlled release is produced from a composition comprising a granular material having a mean particle diameter of 150 to 350 micrometers and a compactibility resulting in a compact with a tensile strength of at least 1.7 MPa when the granular material is subjected to a compaction pressure of 266 MPa, at least 80 percent of the granular material being a water-soluble cellulose ether, water-soluble cellulose ester, an alkylene oxide homo- or copolymer, or a blend thereof； and an active ingredient.
