Anh Tuan PHAN,Christopher Brian Henry Jacques LECH
申请号:
US14787166
公开号:
US20160310519A1
申请日:
2014.04.28
申请国别(地区):
US
年份:
2016
代理人:
摘要:
This invention relates to a nucleic acid nanoparticle comprising at least one G-quadruplex structure wherein at least one guanine base comprises a modification in the N2-position and the use of said nucleic acid nanoparticle as a medicament, molecular sensor, or tag. Further this invention relates to methods of stabilizing a nucleic acid nanoparticle comprising at least one G-quadruplex structure.