The present invention includes an apparatus for transdermal treatmentscomprising: an openableenclosure for a subject in communication with three or more sources oftreatment modalitiesselected from: a source of ozone； a source of steam, a source of CO2 /Carbonic Acid； a sourceof Far Infrared； and a source of pulsed electromagnetic fields (PEMF), whereineach of the threeor more sources is in communication with an interior of the openable enclosureto treat thesubject transdermally.
