PROCESS OF PREPARING LOW ABUK OXYMORPHONE HYDROCHLORIDE

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专利权人:

发明人:

Saroop Matharu,Brian Heinrich,Aniruddh Singh,Mahmoud Mirmehrabi

申请号：

US14608544

公开号：

US20160220560A1

申请日:

2015.01.29

申请国别(地区):

US

年份:

2016

代理人:

摘要：

An improved method for the preparation of the low ABUK oxymorphone hydrochloride is provided. The oxymorphone hydrochloride is produced by hydrogenating a starting material comprising oxymorphone base and 14-hydroxymorphinone in a mixture comprising an alcohol, water and an acid, removing some of the water and adding more alcohol to the mixture.

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中国工程科技知识中心

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