The compounds of a certain formula 1, in which R1, R10, R11, A and R12 have the meanings as given in the description, are novel effective inhibitors of the type 4 phosphodiesterase.本發明係關於一種特定式1之化合物,其中R1、R10、R11、A及R12具有在說明書中給出之含義,該等化合物為4型磷酸二酯酶之新穎有效抑制劑。