Yoram Vodovotz,Alexey Solovyev,David Okonkwo,Maxim Mikheev,Qi Mi,Jorg Gerlach,Gregory M Constantine
申请号：
US14301734
公开号：
US20140350527A1
申请日:
2014.06.11
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A bioreactor is provided which contains cells capable of producing cytokine inhibitors in response to cytokines, in a manner regulated by the local or systemic milieu of an individual patient and predicted by mechanistic computational simulations. The bioreactor transfers the cytokine inhibitors to a patient in need of control of the inflammation process as part of a disease or condition in the patient, such as sepsis, trauma, traumatic brain injury, or wound healing. Related methods also are provided.
