Palli, Subba Reddy,Kumar, Mohan Basavaraju,Cress, Dean Ervin,Fujimoto, Ted Tsutomu
申请号:
EP20100180799
公开号:
EP2275558(B1)
申请日:
2002.02.20
申请国别(地区):
欧洲专利局
年份:
2018
代理人:
摘要:
This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More specifically, this invention relates to novel substitution mutant receptors and their use in a Group H nuclear receptor-based inducible gene expression system and methods of modulating the expression of a gene in a host cell for applications such as gene therapy, large scale production of proteins and antibodies, cell-based high throughput screening assays, functional genomics and regulation of traits in transgenic organisms.