Patrick Y. Lu,David M. Evans,John J. Xu,Alan Y. Lu,Qing Ge
申请号:
US14418432
公开号:
US20160068843A1
申请日:
2013.07.07
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to compositions and methods for development of resistance-proof siRNA therapeutics for prevention and treatment of influenza viral infections. The compositions include a pharmaceutical composition comprising siRNA molecules that target conserved regions of an influenza virus gene and a pharmaceutically acceptable polymeric carrier. In one embodiment, the polymeric carrier condenses the molecules to form a nanoparticle.