Frank Bedu-Addo,Greg Conn,Martin Ward,Jerold Woodward
申请号:
US15724818
公开号:
US20180094032A1
申请日:
2017.10.04
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Novel human papillomovirus immunogenic compositions and methods of use thereof are provided. The compositions comprise unique combinations of multi-epitope peptide sequences specifically selected and designed to be effectively processed and cross-presented to T-cells. The peptides utilized in the compositions display high levels of binding with HLA-supertypes. The immunogenic compositions are broadly applicable to large proportions of target populations. The compositions comprise adjuvants such as cationic lipids.