James C. Paulson,Weihsu Claire Chen,Norihito Kawasaki,Corwin Nycholat
申请号：
US13261581
公开号：
US20130164364A1
申请日:
2011.07.29
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides liposome targeting compounds for targeting cells expressing sialic acid binding Ig-like lectin (Siglec). The liposome compounds typically comprise a binding moiety that is a glycan ligand of the Siglec on the target cell. The liposome compounds also incorporate or encapsulate a biological agent (e.g., an antigen or a therapeutic agent) that can be delivered to the target cell to modulate or kill the target cell. The invention also provides methods of using the liposome targeting compounds for targeted delivery of antigen and for modulating immune cells or immune responses.
