UTILISATION D'INHIBITEURS DE CASPASE-3 ET D'ACTIVATEURS DE CASPASE-3 DANS LA FABRICATION D'UN MÉDICAMENT POUR LE TRAITEMENT DU CANCER ET DE LA CICATRISATION DES PLAIES
Technion Research & Development Foundation Limited
发明人:
FUCHS, Yaron,YOSEFZON, Yahav,SOTERIOU, Despina
申请号:
EP17860888
公开号:
EP3525791A4
申请日:
2017.10.13
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
Provided are methods of selecting a treatment for a cancer in a subject in need thereof, by analyzing activity of Yes associated protein 1 (YAP) in cancer cells of the subject, and methods of treating cancer using a therapeutically effective amount of an caspase-3 inhibitor. Also provided are methods of improving wound healing by administering a wound healing effective amount of a caspase-3 activator.