A method of ultrasound nonlinear imaging with Golay code excitation includes transmitting a first and a second Golay code signal wave which are orthogonal by each other making the second Golay code signal wave be subtracted from the first Golay code signal wave to eliminate a first and a second noise interference wave to generate a third Golay code signal wave using a first and a second compression filter to process the third Golay code signal wave to generate a first and a second compressed code signal wave taking the difference between the first compressed code signal wave and the second compressed code signal wave to generate a third compressed code signal wave which includes at least two second-order harmonic waves processing ultrasound nonlinear imaging by using the multi-frequency harmonic component waves to generate an ultrasound image.
