John Matsoukas,Theodoros Tselios,Vasso Apostolopoulos,Vivian Tseveleki,Maria Katsara,Lesley Probert
申请号：
US14877679
公开号：
US20160095935A1
申请日:
2015.10.07
申请国别(地区):
US
年份:
2016
代理人:
摘要：
A first aspect of the invention relates to a conjugate including mannan and at least one epitope comprising a peptide fragment of a protein selected from myelin basic protein (MBP), myelin oligodentrocyte glycoprotein (MOG) and proteolipid protein (PLP), said peptide fragment being in linear or cyclic form and wherein said epitope is linked to mannan via a [(Lys-Gly)n] bridge, where n is an integer from 1 to 10.Further aspects of the invention relate to pharmaceutical compositions comprising said conjugates, and their use in the preparation of a medicament for treating an immune disorder.
