XIAO, HAI-YUN,DHAR, T.G. MURALI,DUAN, JINGWU,JIANG, BIN,TEBBEN, ANDREW J.
申请号：
CA2980159
公开号：
CA2980159A1
申请日:
2016.03.17
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
Disclosed are compounds of Formula (I) or a salt thereof, wherein: X is N； W is: (i) -(CR3R3)1-4-； (ii)-(CR3R3)x-Y-(CR3R3)y-； or (iii) -Y-(CR3R3)2-Y-； and Y, R1, R2, R3, R5, R6, R8, x, and y are defined herein. Also disclosed are methods of using such compounds as modulators of TNFa, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.
