The invention refers to a cucumber or variant that combines with one or more molecules in a larger histocompatibility (MHC) complex and / or induces a cross reaction of T-lymphocytes with the cucumber. It also refers to pharmacological components, nucleic acids, expression vectors, host cells, appropriate compounds for recognizing these cucumbers and immunotherapy methods for such cucumbers, as well as methods for producing individual anti-cancer vaccines.La invencion se refiere a un peptido o variantes que se unen a una o varias moleculas del complejo mayor de histocompatibilidad (MHC) y/o inducen la reaccion cruzada de linfocitos T con dicho peptido. Tambien se refiere a composiciones farmaceuticas, acidos nucleicos, vectores de expresion, celulas hospedadoras, aptameros que reconocen dichos peptidos y metodos de uso inmunoterapeutico de tales peptidos, asi como metodos para producir una vacuna personalizada contra el cancer